Endocrine Abstracts

Introduction: Insulinomas are rare pancreatic neuroendocrine tumours (PETS), which are usually benign and sporadic. They secrete insulin, and hence present with hypoglycaemia. We report a case of insulinoma presenting as seizures.Case Presentation: The patient, a 16-year-old female, first had an episode of convulsion a year prior to referral to the Endocrine Clinic. She was managed at a private clinic with intravenous fluid (name unknown) and later comme...

Background: Diabetes Mellitus (DM) is a metabolic disorder characterized by elevated blood glucose with accompanying microvascular and macrovascular complications resulting in increased morbidity, mortality and reduce quality of life in an individual living with the disease. Studies have shown that tight glycaemic control contributes immensely to the reduce risk of microvascular complications, and to a certain extent macrovascular complications. Achieving tight glycaemic contr...

Background: Diabetic foot disease is a major cause of morbidity and mortality in people living with diabetes. It is a leading cause of minor or major limb loss with attendant huge economic ruins. Objective: The aim of the study was to determine pattern of presentation of diabetic foot ulcer (DFU), assess co-morbid conditions at admission and determine the overall outcome of patients managed over the 5 year study period. Materials a...

Background and objective: Diabetes mellitus is assuming worldwide increase with Doctors not being an exception. This study was carried out among Doctors in Ondo State South West Nigeria to assess 10 years risk of developing Diabetes using the Finish Diabetes Association assessment form.Subjects, materials and method: This is a cross sectional study carried out in March 2019 at the Ordinary General Meeting. Two hundred and two (202) Doctors were screened ...

Background: Diabetes mellitus worldwide prevalence has risen significantly in the last two decades and type 2 diabetes mellitus makes up 90%. The control of this disease would largely be influenced by improved knowledge among the populace.Objective: To assess the knowledge, attitude and practice on prevention of type 2 diabetes mellitus among undergraduate at Ile Ife.Methods: A cross-sectional survey using simple random sampling te...

Background: Peripheral arterial disease is a disorder due to obstruction of blood supply to extremities. Diabetes mellitus and hypertension are predisposing factors.Objective: To determine if the presence of concurrent hypertension increases the risk of peripheral arterial disease (PAD) in Nigerians with type 2 diabetes.Methods: This was a cross-sectional study that included 160 persons living with diabetes mellitus (60 subjects ha...

Many studies and treatment guidelines have emphasized that the treatment of DM extends beyond glycaemic control, but include lowering lipids, and blood pressure in people living with DM. According to The Task Force on Diabetes and Cardiovascular Disease of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD), dyslipidaemia is strongly related to increased CVD risk. This study determined the prevalence of dyslipidaemia in Typ...

Vitamin D deficiency is associated with the development of some cancers and in vitro 1,25-dihydroxyvitamin D (1,25D) reduces cell proliferation. We suggest that modification of tissue specific immune responses, as a consequence of local synthesis of 1,25D, may be key. To assess the impact of serum 25D on the risk of bladder cancer we conducted a systematic review. To test our hypothesis, expression of vitamin D signalling components and the synthesis of 1,25D were exa...

Background and objectives: Hyperglycaemic emergencies (HE) are the most common acute complication of diabetes and are associated with relative or absolute insulin deficiency, volume depletion, impaired mental status and metabolic derangements. Hyperglycaemic emergencies are associated with high morbidity and mortality if not properly managed. We investigated the pattern of hyperglycaemic emergencies at Obafemi Awolowo University Teaching Hospital, Ile-Ife, South-western Nigeri...

Background: Diabetes mellitus (DM), which is on the increase in developing country like Nigeria, increases the risk of tuberculosis (TB). This study was carried out to detect TB in DM patient attending medical outpatient unit in State Specialist Hospital, Akure South West, Nigeria.Method: This was a cross-sectional study in which six hundred and forty eight DM patients attending the outpatient clinic were consecutively recruited after an informed consent...